Sæson
Episode
- Episode 1: LA X (1)
- Episode 2: LA X (2)
- Episode 3: What Kate Does
- Episode 4: The Substitute
- Episode 5: Lighthouse
- Episode 6: Sundown
- Episode 7: Dr. Linus
- Episode 8: Recon
- Episode 9: Ab Aeterno
- Episode 10: The Package
- Episode 11: Happily Ever After
- Episode 12: Everybody Loves Hugo
- Episode 13: The Last Recruit
- Episode 14: The Candidate
- Episode 15: Across the Sea
- Episode 16: What They Died For
- Episode 17: The End
Lost Sæson 6 The Substitute
Oceanic Flight 815 – et kommercielt fly fra Sydney, Australien til Los Angeles, USA – styrter ned på en tropisk Stillehavsø. De 48 overlevende havner på en ø med mange hemmeligheder, må de holde sammen hvis de nogensinde skal komme hjem i live.
